Open QC,
Create a new Subject in Test Plan
Then place all your QTP scripts in folder
Open QTP and file - > Quality Center Connection
Enter url
Connect
Enter QC UserID and Password
Project : Domain & Project
Open the script you wish to run, click on File - > Save As ....select Quality Center button in the right botton corner
Seelct the relevant subject folder created before in QC
Click on OK
Login to QC, in Test lab, select the testscripts uploaded and click on Run